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Up-regulation of METCAM/MUC18 promotes motility, invasion, and tumorigenesis of human breast cancer cells

BACKGROUND: Conflicting research has identified METCAM/MUC18, an integral membrane cell adhesion molecule (CAM) in the Ig-like gene super-family, as both a tumor promoter and a tumor suppressor in the development of breast cancer. To resolve this, we have re-investigated the role of this CAM in the...

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Detalles Bibliográficos
Autores principales: Zeng, Guo-fang, Cai, Shao-xi, Wu, Guang-Jer
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3079690/
https://www.ncbi.nlm.nih.gov/pubmed/21450088
http://dx.doi.org/10.1186/1471-2407-11-113