Absence of Ataxin-3 Leads to Enhanced Stress Response in C. elegans

Ataxin-3, the protein involved in Machado-Joseph disease, is able to bind ubiquitylated substrates and act as a deubiquitylating enzyme in vitro, and it has been involved in the modulation of protein degradation by the ubiquitin-proteasome pathway. C. elegans and mouse ataxin-3 knockout models are v...

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Detalles Bibliográficos
Autores principales: Rodrigues, Ana João, Neves-Carvalho, Andreia, Teixeira-Castro, Andreia, Rokka, Anne, Corthals, Garry, Logarinho, Elsa, Maciel, Patrícia
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3079722/
https://www.ncbi.nlm.nih.gov/pubmed/21526185
http://dx.doi.org/10.1371/journal.pone.0018512

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3079722/
https://www.ncbi.nlm.nih.gov/pubmed/21526185
http://dx.doi.org/10.1371/journal.pone.0018512

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