Artificial Modulation of the Gating Behavior of a K(+) Channel in a KvAP-DNA Chimera

We present experiments where the gating behavior of a voltage-gated ion channel is modulated by artificial ligand binding. We construct a channel-DNA chimera with the KvAP potassium channel reconstituted in an artificial membrane. The channel is functional and the single channel ion conductivity unp...

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Detalles Bibliográficos
Autores principales: Wang, Andrew, Zocchi, Giovanni
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3079724/
https://www.ncbi.nlm.nih.gov/pubmed/21526187
http://dx.doi.org/10.1371/journal.pone.0018598

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3079724/
https://www.ncbi.nlm.nih.gov/pubmed/21526187
http://dx.doi.org/10.1371/journal.pone.0018598

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