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Artificial Modulation of the Gating Behavior of a K(+) Channel in a KvAP-DNA Chimera
We present experiments where the gating behavior of a voltage-gated ion channel is modulated by artificial ligand binding. We construct a channel-DNA chimera with the KvAP potassium channel reconstituted in an artificial membrane. The channel is functional and the single channel ion conductivity unp...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3079724/ https://www.ncbi.nlm.nih.gov/pubmed/21526187 http://dx.doi.org/10.1371/journal.pone.0018598 |