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Differential Expressions of Adhesive Molecules and Proteases Define Mechanisms of Ovarian Tumor Cell Matrix Penetration/Invasion

Epithelial ovarian cancer is an aggressive and deadly disease and understanding its invasion mechanisms is critical for its treatment. We sought to study the penetration/invasion of ovarian tumor cells into extracellular matrices (ECMs) using a fibroblast-derived three-dimensional (3D) culture model...

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Detalles Bibliográficos
Autores principales: Kwon, Youngjoo, Cukierman, Edna, Godwin, Andrew K.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3079735/
https://www.ncbi.nlm.nih.gov/pubmed/21526198
http://dx.doi.org/10.1371/journal.pone.0018872