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Hepatitis C Virus Protects Human B Lymphocytes from Fas-Mediated Apoptosis via E2-CD81 Engagement

HCV infection is often associated with B-cell regulatory control disturbance and delayed appearance of neutralizing antibodies. CD81 is a cellular receptor for HCV and can bind to HCV envelope protein 2 (E2). CD81 also participates to form a B cell costimulatory complex. To investigate whether HCV i...

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Detalles Bibliográficos
Autores principales: Chen, Zhihui, Zhu, Yongzhe, Ren, Yanli, Tong, Yimin, Hua, Xian, Zhu, Fenghui, Huang, Libin, Liu, Yuan, Luo, Yuan, Lu, Wei, Zhao, Ping, Qi, Zhongtian
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3079738/
https://www.ncbi.nlm.nih.gov/pubmed/21526201
http://dx.doi.org/10.1371/journal.pone.0018933