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Retromer terminates the generation of cAMP by internalized PTH-receptors

Generation of cAMP by G protein–coupled receptors (GPCRs) and its termination is currently thought to occur exclusively at the plasma membrane of cells. Under existing models of receptor regulation, this signal is primarily restricted by desensitizationof the receptors through their binding to β-arr...

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Detalles Bibliográficos
Autores principales: Feinstein, Timothy N., Wehbi, Vanessa L., Ardura, Juan, Wheeler, David S., Ferrandon, Sebastien, Gardella, Thomas J., Vilardaga, Jean-Pierre
Formato: Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3079799/
https://www.ncbi.nlm.nih.gov/pubmed/21445058
http://dx.doi.org/10.1038/nchembio.545