Structure of recombinant Leishmania donovani pteridine reductase reveals a disordered active site

Pteridine reductase (PTR1) is a potential target for drug development against parasitic Trypanosoma and Leishmania species, protozoa that are responsible for a range of serious diseases found in tropical and subtropical parts of the world. As part of a structure-based approach to inhibitor developme...

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Detalles Bibliográficos
Autores principales: Barrack, Keri L., Tulloch, Lindsay B., Burke, Lynsey-Ann, Fyfe, Paul K., Hunter, William N.
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2010
Materias:
Structural Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3079966/
https://www.ncbi.nlm.nih.gov/pubmed/21206018
http://dx.doi.org/10.1107/S174430911004724X

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3079966/
https://www.ncbi.nlm.nih.gov/pubmed/21206018
http://dx.doi.org/10.1107/S174430911004724X

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