Tara up-regulates E-cadherin transcription by binding to the Trio RhoGEF and inhibiting Rac signaling

The spatiotemporal regulation of E-cadherin expression is important during body plan development and carcinogenesis. We found that Tara (Trio-associated repeat on actin) is enriched in cadherin-based adherens junctions (AJs), and its knockdown in MDCK cells (Tara-KD cells) significantly decreases th...

Descripción completa

Detalles Bibliográficos
Autores principales: Yano, Tomoki, Yamazaki, Yuji, Adachi, Makoto, Okawa, Katsuya, Fort, Philippe, Uji, Masami, Tsukita, Shoichiro, Tsukita, Sachiko
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080255/
https://www.ncbi.nlm.nih.gov/pubmed/21482718
http://dx.doi.org/10.1083/jcb.201009100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080255/
https://www.ncbi.nlm.nih.gov/pubmed/21482718
http://dx.doi.org/10.1083/jcb.201009100

Ejemplares similares