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Investigation of tumor hypoxia using a two-enzyme system for in vitro generation of oxygen deficiency
BACKGROUND: Oxygen deficiency in tumor tissue is associated with a malign phenotype, characterized by high invasiveness, increased metastatic potential and poor prognosis. Hypoxia chambers are the established standard model for in vitro studies on tumor hypoxia. An enzymatic hypoxia system (GOX/CAT)...
Autores principales: | , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080288/ https://www.ncbi.nlm.nih.gov/pubmed/21477371 http://dx.doi.org/10.1186/1748-717X-6-35 |