Comparative transcriptome profiling of amyloid precursor protein family members in the adult cortex

BACKGROUND: The β-amyloid precursor protein (APP) and the related β-amyloid precursor-like proteins (APLPs) undergo complex proteolytic processing giving rise to several fragments. Whereas it is well established that Aβ accumulation is a central trigger for Alzheimer's disease, the physiologica...

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Detalles Bibliográficos
Autores principales: Aydin, Dorothee, Filippov, Mikhail A, Tschäpe, Jakob-Andreas, Gretz, Norbert, Prinz, Marco, Eils, Roland, Brors, Benedikt, Müller, Ulrike C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080314/
https://www.ncbi.nlm.nih.gov/pubmed/21435241
http://dx.doi.org/10.1186/1471-2164-12-160

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080314/
https://www.ncbi.nlm.nih.gov/pubmed/21435241
http://dx.doi.org/10.1186/1471-2164-12-160

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