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Comparative transcriptome profiling of amyloid precursor protein family members in the adult cortex

BACKGROUND: The β-amyloid precursor protein (APP) and the related β-amyloid precursor-like proteins (APLPs) undergo complex proteolytic processing giving rise to several fragments. Whereas it is well established that Aβ accumulation is a central trigger for Alzheimer's disease, the physiologica...

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Detalles Bibliográficos
Autores principales:	Aydin, Dorothee, Filippov, Mikhail A, Tschäpe, Jakob-Andreas, Gretz, Norbert, Prinz, Marco, Eils, Roland, Brors, Benedikt, Müller, Ulrike C
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080314/ https://www.ncbi.nlm.nih.gov/pubmed/21435241 http://dx.doi.org/10.1186/1471-2164-12-160

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