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A Kallikrein 15 (KLK15) single nucleotide polymorphism located close to a novel exon shows evidence of association with poor ovarian cancer survival

BACKGROUND: KLK15 over-expression is reported to be a significant predictor of reduced progression-free survival and overall survival in ovarian cancer. Our aim was to analyse the KLK15 gene for putative functional single nucleotide polymorphisms (SNPs) and assess the association of these and KLK15...

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Detalles Bibliográficos
Autores principales: Batra, Jyotsna, Nagle, Christina M, O'Mara, Tracy, Higgins, Melanie, Dong, Ying, Tan, Olivia L, Lose, Felicity, Skeie, Lene Marie, Srinivasan, Srilakshmi, Bolton, Kelly L, Song, Honglin, Ramus, Susan J, Gayther, Simon A, Pharoah, Paul DP, Kedda, Mary-Anne, Spurdle, Amanda B, Clements, Judith A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080344/
https://www.ncbi.nlm.nih.gov/pubmed/21457553
http://dx.doi.org/10.1186/1471-2407-11-119