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Vascular normalization in orthotopic glioblastoma following intravenous treatment with lipid-based nanoparticulate formulations of irinotecan (Irinophore C™), doxorubicin (Caelyx(®)) or vincristine

BACKGROUND: Chemotherapy for glioblastoma (GBM) patients is compromised in part by poor perfusion in the tumor. The present study evaluates how treatment with liposomal formulation of irinotecan (Irinophore C™), and other liposomal anticancer drugs, influence the tumor vasculature of GBM models grow...

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Detalles Bibliográficos
Autores principales: Verreault, Maite, Strutt, Dita, Masin, Dana, Anantha, Malathi, Yung, Andrew, Kozlowski, Piotr, Waterhouse, Dawn, Bally, Marcel B, Yapp, Donald T
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080346/
https://www.ncbi.nlm.nih.gov/pubmed/21477311
http://dx.doi.org/10.1186/1471-2407-11-124