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Chronic Delivery of Antibody Fragments Using Immunoisolated Cell Implants as a Passive Vaccination Tool

BACKGROUND: Monoclonal antibodies and antibody fragments are powerful biotherapeutics for various debilitating diseases. However, high production costs, functional limitations such as inadequate pharmacokinetics and tissue accessibility are the current principal disadvantages for broadening their us...

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Detalles Bibliográficos
Autores principales: Marroquin Belaunzaran, Osiris, Cordero, Maria Isabel, Setola, Veronica, Bianchi, Siro, Galli, Carmela, Bouche, Nicolas, Mlynarik, Vladimir, Gruetter, Rolf, Sandi, Carmen, Bensadoun, Jean-Charles, Molinari, Maurizio, Aebischer, Patrick
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080361/
https://www.ncbi.nlm.nih.gov/pubmed/21533130
http://dx.doi.org/10.1371/journal.pone.0018268