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Chronic Delivery of Antibody Fragments Using Immunoisolated Cell Implants as a Passive Vaccination Tool
BACKGROUND: Monoclonal antibodies and antibody fragments are powerful biotherapeutics for various debilitating diseases. However, high production costs, functional limitations such as inadequate pharmacokinetics and tissue accessibility are the current principal disadvantages for broadening their us...
Autores principales: | Marroquin Belaunzaran, Osiris, Cordero, Maria Isabel, Setola, Veronica, Bianchi, Siro, Galli, Carmela, Bouche, Nicolas, Mlynarik, Vladimir, Gruetter, Rolf, Sandi, Carmen, Bensadoun, Jean-Charles, Molinari, Maurizio, Aebischer, Patrick |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080361/ https://www.ncbi.nlm.nih.gov/pubmed/21533130 http://dx.doi.org/10.1371/journal.pone.0018268 |
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