TLR2-Dependent Induction of IL-10 and Foxp3(+)CD25(+)CD4(+) Regulatory T Cells Prevents Effective Anti-Tumor Immunity Induced by Pam2 Lipopeptides In Vivo

16 S-[2,3-bis(palmitoyl)propyl]cysteine (Pam2) lipopeptides act as toll-like receptor (TLR)2/6 ligands and activate natural killer (NK) cells and dendritic cells (DCs) to produce inflammatory cytokines and cytotoxic NK activity in vitro. However, in this study, we found that systemic injection of Pa...

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Detalles Bibliográficos
Autores principales: Yamazaki, Sayuri, Okada, Kohei, Maruyama, Akira, Matsumoto, Misako, Yagita, Hideo, Seya, Tsukasa
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080372/
https://www.ncbi.nlm.nih.gov/pubmed/21533081
http://dx.doi.org/10.1371/journal.pone.0018833

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080372/
https://www.ncbi.nlm.nih.gov/pubmed/21533081
http://dx.doi.org/10.1371/journal.pone.0018833

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