Cargando…

The Cytoplasmic Domain of MUC1 Induces Hyperplasia in the Mammary Gland and Correlates with Nuclear Accumulation of β-Catenin

MUC1 is an oncoprotein that is overexpressed in up to 90% of breast carcinomas. A previous in vitro study by our group demonstrated that the cytoplasmic domain of MUC1 (MUC1-CD), the minimal functional unit of MUC1, contributes to the malignant phenotype in cells by binding directly to β-catenin and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Yuan, Yi, Haiying, Yao, Yixin, Liao, Xiaodong, Xie, Yiqun, Yang, Jie, Yan, Zheng, Wang, Long, Lu, Shunyuan, Kuang, Ying, Gu, Mingmin, Fei, Jian, Wang, Zhugang, Huang, Lei
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080410/ https://www.ncbi.nlm.nih.gov/pubmed/21533058 http://dx.doi.org/10.1371/journal.pone.0019102

Ejemplares similares

The MUC1 Cytoplasmic Tail and Tandem Repeat Domains Contribute to Mammary Oncogenesis in FVB Mice
por: Hattrup, Christine L., et al.
Publicado: (2008)

Anti-hyperplasia Effects of Total Saponins From Phytolaccae Radix in Rats With Mammary Gland Hyperplasia via Inhibition of Proliferation and Induction of Apoptosis
por: Li, Xiaoliang, et al.
Publicado: (2018)

The Infrared Radiation Temperature Characteristic of Acupoints of Mammary Gland Hyperplasia Patients
por: Zheng, Juanjuan, et al.
Publicado: (2013)

MUC1 induces M2 type macrophage influx during postpartum mammary gland involution and triggers breast cancer
por: Li, Yuan, et al.
Publicado: (2017)

Diminished milk fat secretion and premature mammary gland involution in episialin/MUC1 transgenic mice
por: Wesseling, J, et al.
Publicado: (2001)

Acupuncture for mammary gland hyperplasia: A Bayesian network meta-analysis protocol
por: Xiong, Jun, et al.
Publicado: (2020)

Key signaling nodes in mammary gland development and cancer: β-catenin
por: Incassati, Angela, et al.
Publicado: (2010)

Effects of Atractylodes Macrocephala Rhizoma polysaccharide on intestinal microbiota composition in rats with mammary gland hyperplasia
por: Ping, Yang, et al.
Publicado: (2023)

The Modulatory Properties of Li-Ru-Kang Treatment on Hyperplasia of Mammary Glands Using an Integrated Approach
por: Wei, Shizhang, et al.
Publicado: (2018)

Nuclear-Cytoplasmic Shuttling of Chibby Controls β-Catenin Signaling
por: Li, Feng-Qian, et al.
Publicado: (2010)

Mechanisms of single herbs and herbal pairs in the treatment of mammary gland hyperplasia: An integrated review()
por: Yang, Xujie, et al.
Publicado: (2023)

MUC16 impacts tumor proliferation and migration through cytoplasmic translocation of P120-catenin in epithelial ovarian cancer cells: an original research
por: Chen, Xin, et al.
Publicado: (2019)

Molecular Targets and Associated Potential Pathways of Danlu Capsules in Hyperplasia of Mammary Glands Based on Systems Pharmacology
por: Huang, Jihan, et al.
Publicado: (2017)

A Study of Using Massage Therapy Accompanied with Stretching Exercise for Rehabilitation of Mammary Gland Hyperplasia
por: Lv, Pin, et al.
Publicado: (2016)

MicroRNA array analysis of the regulation of microRNAs in rats exhibiting hyperplasia of mammary glands
por: Gu, Liyan, et al.
Publicado: (2018)

Massage treatment of hyperplasia of mammary glands: A protocol for a systematic review and meta-analysis
por: Ma, Dehui, et al.
Publicado: (2020)

Clinical efficacy of “Sancai therapy” for hyperplasia of the mammary glands: A systematic review and meta-analysis
por: Zhang, Hua, et al.
Publicado: (2023)

Effect of auricular point pressing therapy on hyperplasia of mammary glands: A protocol for systematic review and meta-analysis
por: Ma, Mengjie, et al.
Publicado: (2021)

Construction of microneedle of Atractylodes macrocephala Rhizoma aqueous extract and effect on mammary gland hyperplasia based on intestinal flora
por: Ping, Yang, et al.
Publicado: (2023)

TBX3 over-expression causes mammary gland hyperplasia and increases mammary stem-like cells in an inducible transgenic mouse model
por: Liu, Jing, et al.
Publicado: (2011)

Modulatory Effect of Fermented Papaya Extracts on Mammary Gland Hyperplasia Induced by Estrogen and Progestin in Female Rats
por: You, Zhenqiang, et al.
Publicado: (2017)

Hereditary and breastfeeding factors are positively associated with the aetiology of mammary gland hyperplasia: a case–control study
por: Gao, Hanlu, et al.
Publicado: (2020)

Evaluation of the mechanism of Rujiling capsules in the treatment of hyperplasia of mammary glands based on network pharmacology and molecular docking
por: Shi, Mili, et al.
Publicado: (2022)

Commentary: Anti-hyperplasia effects of total saponins from phytolaccae radix in rats with mammary gland hyperplasia via inhibition of proliferation and induction of apoptosis
por: Cai, Liying, et al.
Publicado: (2023)

Δn89β-Catenin Induces Precocious Development, Differentiation, and Neoplasia in Mammary Gland
por: Imbert, Alexandra, et al.
Publicado: (2001)

Expression of MUC1, MUC2 and MUC5AC in salivary gland mucoepidermoid carcinoma: A case series with diagnostic implications
por: Sood, Neelam, et al.
Publicado: (2022)

Characterization of the MUC1-C Cytoplasmic Domain as a Cancer Target
por: Raina, Deepak, et al.
Publicado: (2015)

Tumors of the mammary gland
por: Rosen, Paul Peter
Publicado: (1993)

Mammary gland neoplasia.
por: Neumann, D A, et al.
Publicado: (1996)

Tuberculosis of the Mammary Gland
por: Goyle, Amar Nath, et al.
Publicado: (1935)

Tumor in Mammary Gland
Publicado: (1872)

Anti-Inflammatory Effect of a TCM Formula Li-Ru-Kang in Rats With Hyperplasia of Mammary Gland and the Underlying Biological Mechanisms
por: Wang, Yingying, et al.
Publicado: (2018)

Clinical practice guideline for diagnosis and treatment of hyperplasia of the mammary glands: Chinese Society of Breast Surgery (CSBrS) practice guideline 2021
por: Ma, Wei, et al.
Publicado: (2021)

Dachshund Depletion Disrupts Mammary Gland Development and Diverts the Composition of the Mammary Gland Progenitor Pool
por: Jiao, Xuanmao, et al.
Publicado: (2018)

Chinese massage, Tui Na, combined with herbs improves clinical symptoms and regulates sex hormones in patients with mammary gland hyperplasia
por: Li, Dandan, et al.
Publicado: (2020)

Tau-Mediated Nuclear Depletion and Cytoplasmic Accumulation of SFPQ in Alzheimer's and Pick's Disease
por: Ke, Yazi, et al.
Publicado: (2012)

Nuclear and Cytoplasmic Accumulation of Ep-ICD Is Frequently Detected in Human Epithelial Cancers
por: Ralhan, Ranju, et al.
Publicado: (2010)

EXTRUSION OF NUCLEAR MATERIALS INTO CYTOPLASM IN THE POSTERIOR SILK GLAND CELLS OF SILKWORM, BOMBYX MORI
por: Tashiro, Yutaka, et al.
Publicado: (1968)

MiR-103 Controls Milk Fat Accumulation in Goat (Capra hircus) Mammary Gland during Lactation
por: Lin, Xianzi, et al.
Publicado: (2013)

Wnt signaling activation and mammary gland hyperplasia in MMTV-LRP6 transgenic mice: implication for breast cancer tumorigenesis
por: Zhang, J, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_g4351trv47c66mb1cefop3c8q2