In Autoimmune Diabetes Unique Autoreactive T Cells Recognize Insulin Peptides Generated in the Islets of Langerhans

Besides the genetic framework, there are two critical requirements for the development of tissue-specific autoimmune diseases. First, autoreactive T cells need to escape thymic negative selection. Second, they need to find suitable conditions for autoantigen presentation and activation in the target...

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Detalles Bibliográficos
Autores principales: Mohan, James F., Levisetti, Matteo G., Calderon, Boris, Herzog, Jeremy W., Petzold, Shirley J., Unanue, Emil R.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080751/
https://www.ncbi.nlm.nih.gov/pubmed/20190756
http://dx.doi.org/10.1038/ni.1850

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080751/
https://www.ncbi.nlm.nih.gov/pubmed/20190756
http://dx.doi.org/10.1038/ni.1850

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