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Two common genetic variants near nuclear-encoded OXPHOS genes are associated with insulin secretion in vivo
CONTEXT: Mitochondrial ATP production is important in the regulation of glucose-stimulated insulin secretion. Genetic factors may modulate the capacity of the β-cells to secrete insulin and thereby contribute to the risk of type 2 diabetes. OBJECTIVE: The aim of this study was to identify genetic lo...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioScientifica
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080761/ https://www.ncbi.nlm.nih.gov/pubmed/21325017 http://dx.doi.org/10.1530/EJE-10-0995 |