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Activation of Nuclear Factor-kappa B signalling promotes cellular senescence

Cellular senescence is a program of irreversible cell cycle arrest that normal cells undergo in response to progressive shortening of telomeres, changes in telomeric structure, oncogene activation or oxidative stress. The underlying signalling pathways, of major clinicopathological relevance, are un...

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Detalles Bibliográficos
Autores principales: Rovillain, Emilie, Mansfield, Louise, Caetano, Catia, Alvarez-Fernandez, Monica, Caballero, Otavia L., Medema, Rene H., Hummerich, Holger, Jat, Parmjit S.
Formato: Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080811/
https://www.ncbi.nlm.nih.gov/pubmed/21242976
http://dx.doi.org/10.1038/onc.2010.611