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Activation of Nuclear Factor-kappa B signalling promotes cellular senescence
Cellular senescence is a program of irreversible cell cycle arrest that normal cells undergo in response to progressive shortening of telomeres, changes in telomeric structure, oncogene activation or oxidative stress. The underlying signalling pathways, of major clinicopathological relevance, are un...
Autores principales: | Rovillain, Emilie, Mansfield, Louise, Caetano, Catia, Alvarez-Fernandez, Monica, Caballero, Otavia L., Medema, Rene H., Hummerich, Holger, Jat, Parmjit S. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080811/ https://www.ncbi.nlm.nih.gov/pubmed/21242976 http://dx.doi.org/10.1038/onc.2010.611 |
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