Therapeutic potential of PRL-3 targeting and clinical significance of PRL-3 genomic amplification in gastric cancer

BACKGROUND: Phosphatase of regenerating liver-3 (PRL-3) has deserved attention as a crucial molecule in the multiple steps of metastasis. In the present study, we examined the mechanisms regulating PRL-3 expression, and assessed the clinical potential of PRL-3-targeted therapy in gastric cancer. MET...

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Detalles Bibliográficos
Autores principales: Ooki, Akira, Yamashita, Keishi, Kikuchi, Shiro, Sakuramoto, Shinichi, Katada, Natsuya, Waraya, Mina, Kawamata, Hiroshi, Nishimiya, Hiroshi, Nakamura, Kazunori, Watanabe, Masahiko
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080833/
https://www.ncbi.nlm.nih.gov/pubmed/21466710
http://dx.doi.org/10.1186/1471-2407-11-122

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080833/
https://www.ncbi.nlm.nih.gov/pubmed/21466710
http://dx.doi.org/10.1186/1471-2407-11-122

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