Alterations in PTEN and PIK3CA in colorectal cancers in the EPIC Norfolk study: associations with clinicopathological and dietary factors

BACKGROUND: The PTEN tumour suppressor gene and PIK3CA proto-oncogene encode proteins which contribute to regulation and propagation of signal transduction through the PI3K/AKT signalling pathway. This study investigates the prevalence of loss of PTEN expression and mutations in both PTEN and PIK3CA...

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Detalles Bibliográficos
Autores principales: Naguib, Adam, Cooke, James C, Happerfield, Lisa, Kerr, Lucy, Gay, Laura J, Luben, Robert N, Ball, Richard Y, Mitrou, Panagiota N, McTaggart, Alison, Arends, Mark J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080834/
https://www.ncbi.nlm.nih.gov/pubmed/21473780
http://dx.doi.org/10.1186/1471-2407-11-123

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080834/
https://www.ncbi.nlm.nih.gov/pubmed/21473780
http://dx.doi.org/10.1186/1471-2407-11-123

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