PDP-1 Links the TGF-β and IIS Pathways to Regulate Longevity, Development, and Metabolism

The insulin/IGF-1 signaling (IIS) pathway is a conserved regulator of longevity, development, and metabolism. In Caenorhabditis elegans IIS involves activation of DAF-2 (insulin/IGF-1 receptor tyrosine kinase), AGE-1 (PI 3-kinase), and additional downstream serine/threonine kinases that ultimately p...

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Detalles Bibliográficos
Autores principales: Narasimhan, Sri Devi, Yen, Kelvin, Bansal, Ankita, Kwon, Eun-Soo, Padmanabhan, Srivatsan, Tissenbaum, Heidi A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080858/
https://www.ncbi.nlm.nih.gov/pubmed/21533078
http://dx.doi.org/10.1371/journal.pgen.1001377

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080858/
https://www.ncbi.nlm.nih.gov/pubmed/21533078
http://dx.doi.org/10.1371/journal.pgen.1001377

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