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Enhanced Statistical Tests for GWAS in Admixed Populations: Assessment using African Americans from CARe and a Breast Cancer Consortium

While genome-wide association studies (GWAS) have primarily examined populations of European ancestry, more recent studies often involve additional populations, including admixed populations such as African Americans and Latinos. In admixed populations, linkage disequilibrium (LD) exists both at a f...

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Detalles Bibliográficos
Autores principales: Pasaniuc, Bogdan, Zaitlen, Noah, Lettre, Guillaume, Chen, Gary K., Tandon, Arti, Kao, W. H. Linda, Ruczinski, Ingo, Fornage, Myriam, Siscovick, David S., Zhu, Xiaofeng, Larkin, Emma, Lange, Leslie A., Cupples, L. Adrienne, Yang, Qiong, Akylbekova, Ermeg L., Musani, Solomon K., Divers, Jasmin, Mychaleckyj, Joe, Li, Mingyao, Papanicolaou, George J., Millikan, Robert C., Ambrosone, Christine B., John, Esther M., Bernstein, Leslie, Zheng, Wei, Hu, Jennifer J., Ziegler, Regina G., Nyante, Sarah J., Bandera, Elisa V., Ingles, Sue A., Press, Michael F., Chanock, Stephen J., Deming, Sandra L., Rodriguez-Gil, Jorge L., Palmer, Cameron D., Buxbaum, Sarah, Ekunwe, Lynette, Hirschhorn, Joel N., Henderson, Brian E., Myers, Simon, Haiman, Christopher A., Reich, David, Patterson, Nick, Wilson, James G., Price, Alkes L.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080860/
https://www.ncbi.nlm.nih.gov/pubmed/21541012
http://dx.doi.org/10.1371/journal.pgen.1001371