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The expression of a disintegrin and metalloproteinase with thrombospondin motifs 4 in human macrophages is inhibited by the anti-atherogenic cytokine transforming growth factor-β and requires Smads, p38 mitogen-activated protein kinase and c-Jun

Atherosclerosis is an inflammatory disorder of the vasculature that is orchestrated by the action of cytokines. Macrophages play a prominent role in all stages of this disease, including foam cell formation, production of reactive oxygen species, modulation of the inflammatory response and the regul...

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Detalles Bibliográficos
Autores principales: Salter, Rebecca C., Arnaoutakis, Konstantinos, Michael, Daryn R., Singh, Nishi N., Ashlin, Tim G., Buckley, Melanie L., Kwan, Alvin P.L., Ramji, Dipak P.
Formato: Texto
Lenguaje:English
Publicado: Elsevier 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3081072/
https://www.ncbi.nlm.nih.gov/pubmed/21334453
http://dx.doi.org/10.1016/j.biocel.2011.02.005