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Mitochondrial optic neuropathies – Disease mechanisms and therapeutic strategies

Leber hereditary optic neuropathy (LHON) and autosomal-dominant optic atrophy (DOA) are the two most common inherited optic neuropathies in the general population. Both disorders share striking pathological similarities, marked by the selective loss of retinal ganglion cells (RGCs) and the early inv...

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Detalles Bibliográficos
Autores principales: Yu-Wai-Man, Patrick, Griffiths, Philip G., Chinnery, Patrick F.
Formato: Texto
Lenguaje:English
Publicado: Pergamon 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3081075/
https://www.ncbi.nlm.nih.gov/pubmed/21112411
http://dx.doi.org/10.1016/j.preteyeres.2010.11.002