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The discovery of Hepatocyte Growth Factor (HGF) and its significance for cell biology, life sciences and clinical medicine

It has been more than 25 years since HGF was discovered as a mitogen of hepatocytes. HGF is produced by stromal cells, and stimulates epithelial cell proliferation, motility, morphogenesis and angiogenesis in various organs via tyrosine phosphorylation of its receptor, c-Met. In fetal stages, HGF-ne...

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Detalles Bibliográficos
Autores principales: NAKAMURA, Toshikazu, MIZUNO, Shinya
Formato: Texto
Lenguaje:English
Publicado: The Japan Academy 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3081175/
https://www.ncbi.nlm.nih.gov/pubmed/20551596
http://dx.doi.org/10.2183/pjab.86.588