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Characterization of antibody-mediated neutralization directed against the hypervariable region 1 of hepatitis C virus E2 glycoprotein

The hypervariable region 1 (HVR1) comprising the first 27 aa of E2 glycoprotein is a target for neutralizing antibodies against hepatitis C virus (HCV), but the mechanisms of this neutralization in the cell-culture-infectious genotype 2a strain JFH1 HCV virus (HCVcc) system are unknown. Two rabbit p...

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Detalles Bibliográficos
Autores principales: Vieyres, Gabrielle, Dubuisson, Jean, Patel, Arvind H.
Formato: Texto
Lenguaje:English
Publicado: Society for General Microbiology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3081231/
https://www.ncbi.nlm.nih.gov/pubmed/21084495
http://dx.doi.org/10.1099/vir.0.028092-0