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Towards Accurate Estimation of the Proportion of True Null Hypotheses in Multiple Testing
BACKGROUND: Biomedical researchers are now often faced with situations where it is necessary to test a large number of hypotheses simultaneously, eg, in comparative gene expression studies using high-throughput microarray technology. To properly control false positive errors the FDR (false discovery...
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| Formato: | Texto |
| Lenguaje: | English |
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Public Library of Science
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3081301/ https://www.ncbi.nlm.nih.gov/pubmed/21526119 http://dx.doi.org/10.1371/journal.pone.0018874 |