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A Model for the Evolution of Nucleotide Polymerase Directionality
BACKGROUND: In all known living organisms, every enzyme that synthesizes nucleic acid polymers does so by adding nucleotide 5′-triphosphates to the 3′-hydroxyl group of the growing chain. This results in the well known [Image: see text] directionality of all DNA and RNA Polymerases. The lack of any...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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Public Library of Science
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3081310/ https://www.ncbi.nlm.nih.gov/pubmed/21526126 http://dx.doi.org/10.1371/journal.pone.0018881 |