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A Model for the Evolution of Nucleotide Polymerase Directionality

BACKGROUND: In all known living organisms, every enzyme that synthesizes nucleic acid polymers does so by adding nucleotide 5′-triphosphates to the 3′-hydroxyl group of the growing chain. This results in the well known [Image: see text] directionality of all DNA and RNA Polymerases. The lack of any...

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Detalles Bibliográficos
Autores principales: Ballanco, Joshua, Mansfield, Marc L.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3081310/
https://www.ncbi.nlm.nih.gov/pubmed/21526126
http://dx.doi.org/10.1371/journal.pone.0018881