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A Novel DC Therapy with Manipulation of MKK6 Gene on Nickel Allergy in Mice
BACKGROUND: Although the activation of dermal dendritic cells (DCs) or Langerhans cells (LCs) via p38 mitogen-activated protein kinase (MAPK) plays a crucial role in the pathogenesis of metal allergy, the in vivo molecular mechanisms have not been identified and a possible therapeutic strategy using...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3081319/ https://www.ncbi.nlm.nih.gov/pubmed/21544193 http://dx.doi.org/10.1371/journal.pone.0019017 |