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A Novel DC Therapy with Manipulation of MKK6 Gene on Nickel Allergy in Mice

BACKGROUND: Although the activation of dermal dendritic cells (DCs) or Langerhans cells (LCs) via p38 mitogen-activated protein kinase (MAPK) plays a crucial role in the pathogenesis of metal allergy, the in vivo molecular mechanisms have not been identified and a possible therapeutic strategy using...

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Detalles Bibliográficos
Autores principales: Watanabe, Megumi, Ishimaru, Naozumi, Ashrin, Meinar Nur, Arakaki, Rieko, Yamada, Akiko, Ichikawa, Tetsuo, Hayashi, Yoshio
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3081319/
https://www.ncbi.nlm.nih.gov/pubmed/21544193
http://dx.doi.org/10.1371/journal.pone.0019017