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Progression to AIDS in South Africa Is Associated with both Reverting and Compensatory Viral Mutations
We lack the understanding of why HIV-infected individuals in South Africa progress to AIDS. We hypothesised that in end-stage disease there is a shifting dynamic between T cell imposed immunity and viral immune escape, which, through both compensatory and reverting viral mutations, results in increa...
Autores principales: | , , , , , , , , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3081339/ https://www.ncbi.nlm.nih.gov/pubmed/21544209 http://dx.doi.org/10.1371/journal.pone.0019018 |