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Two-dimensional concurrent HMQC-COSY as an approach for small molecule chemical shift assignment and compound identification

Chemical shift assignment is the first step toward the structure elucidation of natural products and other chemical compounds. We propose here the use of 2D concurrent HMQC-COSY as an experiment for rapid chemical shift assignment of small molecules. This experiment provides well-dispersed (1)H–(13)...

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Detalles Bibliográficos
Autores principales: Hu, Kaifeng, Westler, William M., Markley, John L.
Formato: Texto
Lenguaje:English
Publicado: Springer Netherlands 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3081433/
https://www.ncbi.nlm.nih.gov/pubmed/21373839
http://dx.doi.org/10.1007/s10858-011-9494-4