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Protective effect of a JNK inhibitor against retinal ganglion cell loss induced by acute moderate ocular hypertension

PURPOSE: To correlate retinal ganglion cell (RGC) loss and optic nerve (ON) damage with the duration of acute glaucoma attacks in a rat experimental model and to determine whether the c-Jun N-terminal kinase (JNK) inhibitor SP600125 protects against such attacks. METHODS: To model an acute glaucoma...

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Detalles Bibliográficos
Autores principales: Sun, Hui, Wang, Ying, Pang, Iok-Hou, Shen, Jiaquan, Tang, Xia, Li, Ying, Liu, Chuanyong, Li, Bing
Formato: Texto
Lenguaje:English
Publicado: Molecular Vision 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3081797/
https://www.ncbi.nlm.nih.gov/pubmed/21527996