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Gains, Losses and Changes of Function after Gene Duplication: Study of the Metallothionein Family

Metallothioneins (MT) are small proteins involved in heavy metal detoxification and protection against oxidative stress and cancer. The mammalian MT family originated through a series of duplication events which generated four major genes (MT1 to MT4). MT1 and MT2 encode for ubiquitous proteins, whi...

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Detalles Bibliográficos
Autores principales: Moleirinho, Ana, Carneiro, João, Matthiesen, Rune, Silva, Raquel M., Amorim, António, Azevedo, Luísa
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3081807/
https://www.ncbi.nlm.nih.gov/pubmed/21541013
http://dx.doi.org/10.1371/journal.pone.0018487