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Gains, Losses and Changes of Function after Gene Duplication: Study of the Metallothionein Family
Metallothioneins (MT) are small proteins involved in heavy metal detoxification and protection against oxidative stress and cancer. The mammalian MT family originated through a series of duplication events which generated four major genes (MT1 to MT4). MT1 and MT2 encode for ubiquitous proteins, whi...
Autores principales: | Moleirinho, Ana, Carneiro, João, Matthiesen, Rune, Silva, Raquel M., Amorim, António, Azevedo, Luísa |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3081807/ https://www.ncbi.nlm.nih.gov/pubmed/21541013 http://dx.doi.org/10.1371/journal.pone.0018487 |
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