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Dispersal of Group A Streptococcal Biofilms by the Cysteine Protease SpeB Leads to Increased Disease Severity in a Murine Model

Group A Streptococcus (GAS) is a Gram-positive human pathogen best known for causing pharyngeal and mild skin infections. However, in the 1980's there was an increase in severe GAS infections including cellulitis and deeper tissue infections like necrotizing fasciitis. Particularly striking abo...

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Detalles Bibliográficos
Autores principales: Connolly, Kristie L., Roberts, Amity L., Holder, Robert C., Reid, Sean D.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3081844/
https://www.ncbi.nlm.nih.gov/pubmed/21547075
http://dx.doi.org/10.1371/journal.pone.0018984