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Increasing tumoral 5-fluorouracil concentrations during a 5-day continuous infusion: a microdialysis study
PURPOSE: Response to anticancer therapy is believed to be directly related to the concentration of the anticancer drug in the tumor itself. Assessment of intra-tumor drug pharmacokinetics can be helpful to gain more insight into mechanisms involved in the (in)sensitivity of tumors to anticancer ther...
Autores principales: | , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082021/ https://www.ncbi.nlm.nih.gov/pubmed/20652702 http://dx.doi.org/10.1007/s00280-010-1400-3 |