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Ascorbate exerts anti-proliferative effects through cell cycle inhibition and sensitizes tumor cells towards cytostatic drugs

PURPOSE: While the benefits of ascorbic acid (vitamin C, ascorbate) as an essential nutrient are well established, its effects on tumor cells and in tumor treatment are controversial. In particular, conflicting data exist whether ascorbate may increase the cytotoxic effects of antineoplastic drugs o...

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Detalles Bibliográficos
Autores principales: Frömberg, Anja, Gutsch, Daniela, Schulze, Daniel, Vollbracht, Claudia, Weiss, Gabriele, Czubayko, Frank, Aigner, Achim
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082037/
https://www.ncbi.nlm.nih.gov/pubmed/20694726
http://dx.doi.org/10.1007/s00280-010-1418-6