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Ascorbate exerts anti-proliferative effects through cell cycle inhibition and sensitizes tumor cells towards cytostatic drugs
PURPOSE: While the benefits of ascorbic acid (vitamin C, ascorbate) as an essential nutrient are well established, its effects on tumor cells and in tumor treatment are controversial. In particular, conflicting data exist whether ascorbate may increase the cytotoxic effects of antineoplastic drugs o...
Autores principales: | Frömberg, Anja, Gutsch, Daniela, Schulze, Daniel, Vollbracht, Claudia, Weiss, Gabriele, Czubayko, Frank, Aigner, Achim |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082037/ https://www.ncbi.nlm.nih.gov/pubmed/20694726 http://dx.doi.org/10.1007/s00280-010-1418-6 |
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