Phase I, pharmacokinetic, and biological studies of TSU-68, a novel multiple receptor tyrosine kinase inhibitor, administered after meals with solid tumors

PURPOSE: TSU-68 is a low molecular weight inhibitor of the tyrosine kinases for vascular endothelial growth factor receptor 2, platelet-derived growth factor receptor β, and fibroblast growth factors receptor 1. In this study, we assessed the recommended dose with TSU-68 administration of twice-dail...

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Detalles Bibliográficos
Autores principales: Murakami, Haruyasu, Ueda, Yutaka, Shimoyama, Tatsu, Yamamoto, Noboru, Yamada, Yasuhide, Arioka, Hitoshi, Tamura, Tomohide
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2010
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082038/
https://www.ncbi.nlm.nih.gov/pubmed/20676674
http://dx.doi.org/10.1007/s00280-010-1405-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082038/
https://www.ncbi.nlm.nih.gov/pubmed/20676674
http://dx.doi.org/10.1007/s00280-010-1405-y

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