Functional analysis of the conserved hydrophobic gate region of the magnesium transporter CorA

The Leu294 residue in the cytoplasmic neck of Thermotoga maritima CorA is considered to be the main gate for Mg(2+) transport. We created three site-directed mutants at this position: in the Leu294Asp and Leu294Gly mutants we observed a defect in closing of the pore, while in the Leu294Arg mutant no...

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Detalles Bibliográficos
Autores principales: Svidová, Soňa, Sponder, Gerhard, Schweyen, Rudolf J., Djinović-Carugo, Kristina
Formato: Texto
Lenguaje:English
Publicado: Elsevier Pub. Co 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082049/
https://www.ncbi.nlm.nih.gov/pubmed/21074514
http://dx.doi.org/10.1016/j.bbamem.2010.10.017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082049/
https://www.ncbi.nlm.nih.gov/pubmed/21074514
http://dx.doi.org/10.1016/j.bbamem.2010.10.017

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