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Runx1 modulates adult hair follicle stem cell emergence and maintenance from distinct embryonic skin compartments

Runx1 controls hematopoietic stem cell emergence and hair follicle stem cell (HFSC) activation and proliferation in adult skin. Here we use lineage tracing and mouse genetic manipulation to address the role of Runx1 in the embryonic development of HFSCs. We find Runx1 is expressed in distinct classe...

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Detalles Bibliográficos
Autores principales: Osorio, Karen M., Lilja, Karin C., Tumbar, Tudorita
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082184/
https://www.ncbi.nlm.nih.gov/pubmed/21464233
http://dx.doi.org/10.1083/jcb.201006068