Replication stress induces 53BP1-containing OPT domains in G1 cells

Chromosomal deletions and rearrangements in tumors are often associated with common fragile sites, which are specific genomic loci prone to gaps and breaks in metaphase chromosomes. Common fragile sites appear to arise through incomplete DNA replication because they are induced after partial replica...

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Detalles Bibliográficos
Autores principales: Harrigan, Jeanine A., Belotserkovskaya, Rimma, Coates, Julia, Dimitrova, Daniela S., Polo, Sophie E., Bradshaw, Charles R., Fraser, Peter, Jackson, Stephen P.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082192/
https://www.ncbi.nlm.nih.gov/pubmed/21444690
http://dx.doi.org/10.1083/jcb.201011083

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082192/
https://www.ncbi.nlm.nih.gov/pubmed/21444690
http://dx.doi.org/10.1083/jcb.201011083

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