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A hierarchy of signals regulates entry of membrane proteins into the ciliary membrane domain in epithelial cells
The membrane of the primary cilium is continuous with the plasma membrane but compositionally distinct. Although some membrane proteins concentrate in the cilium, others such as podocalyxin/gp135 are excluded. We found that exclusion reflects a saturable selective retention mechanism. Podocalyxin is...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082196/ https://www.ncbi.nlm.nih.gov/pubmed/21444686 http://dx.doi.org/10.1083/jcb.201009001 |