HTLV-1 Tax Specific CD8+ T Cells Express Low Levels of Tim-3 in HTLV-1 Infection: Implications for Progression to Neurological Complications

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The T cell immunoglobulin mucin 3 (Tim-3) receptor is highly expressed on HIV-1-specific T cells, rendering them partially “exhausted” and unable to contribute to the effective immune mediated control of viral replication. To elucidate novel mechanisms contributing to the HTLV-1 neurological complex...

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Bibliografiska uppgifter
Huvudupphovsmän: Ndhlovu, Lishomwa C., Leal, Fabio E., Hasenkrug, Aaron M., Jha, Aashish R., Carvalho, Karina I., Eccles-James, Ijeoma G., Bruno, Fernanda R., Vieira, Raphaella G. S., York, Vanessa A., Chew, Glen M., Jones, R. Brad, Tanaka, Yuetsu, Neto, Walter K., Sanabani, Sabri S., Ostrowski, Mario A., Segurado, Aluisio C., Nixon, Douglas F., Kallas, Esper G.
Materialtyp: Text
Språk:English
Publicerad: Public Library of Science 2011
Ämnen:
Research Article
Länkar:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082508/
https://www.ncbi.nlm.nih.gov/pubmed/21541358
http://dx.doi.org/10.1371/journal.pntd.0001030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082508/
https://www.ncbi.nlm.nih.gov/pubmed/21541358
http://dx.doi.org/10.1371/journal.pntd.0001030

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