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HTLV-1 Tax Specific CD8+ T Cells Express Low Levels of Tim-3 in HTLV-1 Infection: Implications for Progression to Neurological Complications
The T cell immunoglobulin mucin 3 (Tim-3) receptor is highly expressed on HIV-1-specific T cells, rendering them partially “exhausted” and unable to contribute to the effective immune mediated control of viral replication. To elucidate novel mechanisms contributing to the HTLV-1 neurological complex...
Autores principales: | Ndhlovu, Lishomwa C., Leal, Fabio E., Hasenkrug, Aaron M., Jha, Aashish R., Carvalho, Karina I., Eccles-James, Ijeoma G., Bruno, Fernanda R., Vieira, Raphaella G. S., York, Vanessa A., Chew, Glen M., Jones, R. Brad, Tanaka, Yuetsu, Neto, Walter K., Sanabani, Sabri S., Ostrowski, Mario A., Segurado, Aluisio C., Nixon, Douglas F., Kallas, Esper G. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082508/ https://www.ncbi.nlm.nih.gov/pubmed/21541358 http://dx.doi.org/10.1371/journal.pntd.0001030 |
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