HTLV-1 Tax Specific CD8+ T Cells Express Low Levels of Tim-3 in HTLV-1 Infection: Implications for Progression to Neurological Complications

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The T cell immunoglobulin mucin 3 (Tim-3) receptor is highly expressed on HIV-1-specific T cells, rendering them partially “exhausted” and unable to contribute to the effective immune mediated control of viral replication. To elucidate novel mechanisms contributing to the HTLV-1 neurological complex...

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Detalhes bibliográficos
Principais autores: Ndhlovu, Lishomwa C., Leal, Fabio E., Hasenkrug, Aaron M., Jha, Aashish R., Carvalho, Karina I., Eccles-James, Ijeoma G., Bruno, Fernanda R., Vieira, Raphaella G. S., York, Vanessa A., Chew, Glen M., Jones, R. Brad, Tanaka, Yuetsu, Neto, Walter K., Sanabani, Sabri S., Ostrowski, Mario A., Segurado, Aluisio C., Nixon, Douglas F., Kallas, Esper G.
Formato: Texto
Idioma:English
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082508/
https://www.ncbi.nlm.nih.gov/pubmed/21541358
http://dx.doi.org/10.1371/journal.pntd.0001030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082508/
https://www.ncbi.nlm.nih.gov/pubmed/21541358
http://dx.doi.org/10.1371/journal.pntd.0001030

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